artful solutions to scientific challenges

Capabilities

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Protein production for crystallography and cryo-EM

We are intimately familiar with quality requirements for successful crystallization or EM grid preparation. This includes rational design of protein variants with properties that are desirable for crystallization and EM application. Membrane protein capabilities coming in 2021

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Rare/unusual reagent provision

production scientific reagents that are difficult to obtain through regular channels. We custom make rare enzymes, protein conjugates, synthetic compounds, strains and more to enable your early Discovery and other R&D activities

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Target Exploration and Development

literature and patent analysis, construct design, target expression, proof of function, assay development, and more. We have experience with enzymes, protein interactors, DNA/RNA interactors, ubiquitin ligases and other challenging proteins.

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DNA-encoded library target production

production, characterization, and specific QC of protein targets for DEL (DEX) screening

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Enzymology

assay design de-novo, adaptation of assay pipelines for HT, rare/unusual assays, expanded kinetic profiling of enzymes